What Are Your Chances of Having a Baby With Down Syndrome?

What is the chance that my baby will have Downdifferent chromosome (called a translocation).
syndrome? If you're asking the question, you'reThe genetic cause can be determined by examining
probably pregnant or considering pregnancy.the chromosomes of the child and/or parents. If the
Most people have seen a child with Down syndromemother carries a translocation, the risk for having a
- it's fairly easily to recognize. What people fear isn'tchild with Down syndrome is about 1 in 10. If the
so much the physical problems these children exhibit,father carries the abnormal chromosome, the risk is
but the mental retardation caused by the extraabout 1 in 20. Chromosome testing would not
chromosome #21.normally be performed on parents unless they've
The incidence of Down syndrome increases with thealready had one child with Down syndrome.
age of the mother. Although alcohol and tobacco usePregnant women can be tested to see if their baby
have been linked to other conditions, they are notis likely to have Down syndrome, but this testing
thought to increase the risk of Down syndrome.may or may not be covered by your insurance.
According to the Merck Manual, a time-honoredBecause testing is expensive (hundreds of dollars),
medical reference, the overall risk is 1 in 800.not entirely accurate, and potentially dangerous to
However, for babies born to 20-year-old mothers thethe unborn child, you should talk to your doctor
risk is only 1 in 2000 births. By age 35 the risk rises toabout reasons to perform the test and reasons not
1/365, and at age 40 is about 1%.to.
The answer is a bit more complicated than this,While it's true Down syndrome children suffer from a
however, because not all Down syndrome has thevariety of problems, many are gifted with a great
same genetic cause. Most cases (about 95%) arecapacity for love. Don't let fear blind you to the
due to a second copy of a complete chromosomepossibility of learning more about love than you could
21. The other 5% of cases are due to an extraever imagine.
fragment of chromosome 21 getting stuck on aCopyright 2010 Cynthia J.